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Gene Expression Data
Assay Details
Assay
Reference: J:63747 Zuklys S, et al., Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol. 2000 Aug 15;165(4):1976-83
Assay type: RNA in situ
MGI Accession ID: MGI:5478767
Gene symbol: Aire
Gene name: autoimmune regulator
Probe: Aire cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Present Regionally restricted 2A a Expression is in small but distinct aggregates scattered throughout the entire organ.
Specimen 3A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thymus cortex Present Regionally restricted 3A Expression is at the cortex/medulla junction.
TS28: thymus medullary core Present Punctate 3A
Specimen 4A b: postnatal (more )
Structure Level Pattern Image Note
TS28: thymus Present 4A b
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory