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Gene Expression Data
Assay Details
Assay
Reference: J:184419 Kawashima Y, et al., Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J Clin Invest. 2011 Dec;121(12):4796-809
Assay type: RT-PCR
MGI Accession ID: MGI:5474488
Gene symbol: Tmc1
Gene name: transmembrane channel-like gene family 1
Probe: Tmc1-pA, Tmc1-pB
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Expression levels were normalized first to Actb expression and then to the Tmc expression level at E15. Expression was assessed on different parts of the cochlea: apex, mid-apical, mid-base, and base. Each point was shown on a graph.
Results
Image: 1B Tmc1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
P0 P0 TS27: cochlea Present Not Specified; total RNA Not Specified Not Specified
P1 P1 TS27: cochlea Present Not Specified; total RNA Not Specified Not Specified
P2 P2 TS27: cochlea Present Not Specified; total RNA Not Specified Not Specified
P3 P3 TS27: cochlea Present Not Specified; total RNA Not Specified Not Specified
P4 P4 TS28: cochlea Present Not Specified; total RNA Not Specified Not Specified
P5 P5 TS28: cochlea Present (b) Not Specified; total RNA Not Specified Not Specified
P22 P22 TS28: cochlea Present (c) Not Specified; total RNA Not Specified Not Specified
Notes:
(a) There is a steady rise in expression through P5 and in the P22 apical sample.
(b) Levels increased 20-fold.
(c) More than 200-fold increase in expression.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory