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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446491
Gene symbol: Gdf5
Gene name: growth differentiation factor 5
Probe: Gdf5 probe6
Probe preparation: Antisense RNA labelled with P33
Visualized with: Autoradiography
Results
Specimen 5 Gdf5 14.5 wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit mesenchyme Present Regionally restricted 5_Gdf5 14.5 wt Subject: sclera & lacrimal glan

Specimen 5 Gdf5 14.5 spdh/spdh: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS22: forelimb digit mesenchyme Weak Regionally restricted 5_Gdf5 14.5 spdh/spdh Reduced expression in perichondrium. No expression in interzone.

Specimen 5 Gdf5 16.5 wt: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Present Regionally restricted 5_Gdf5 16.5 wt Expression in perichondrium, joint interzone, and cartilage of joint.

Specimen 5 Gdf5 16.5 spdh/spdh: embryonic day 16.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Weak Regionally restricted 5_Gdf5 16.5 spdh/spdh Reduced expression in perichondrium. No expression in interzone, with the exception of digit 1 and distal interphalangeal joints.

Specimen not shown postnatal wt: postnatal (more )
Structure Level Pattern Image Note
TS28: hand bone Present Regionally restricted Expression in perichondrium, joint interzone, and cartilage of joint.
TS28: hand connective tissue Present Regionally restricted Expression in perichondrium, joint interzone, and cartilage of joint.
TS28: perichondrium Present Regionally restricted Expression in perichondrium, joint interzone, and cartilage of joint.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/05/2021
MGI 6.17
The Jackson Laboratory