About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446474
Gene symbol: Gdf5
Gene name: growth differentiation factor 5
Probe: Gdf5 probe6
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen 2 Gdf5 12.5 wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Regionally restricted 2_Gdf5 12.5 wt/wt Expression in perichondrium of early digital anlage, with a striped pattern of expression in developing joints of digits.

Specimen 2 Gdf5 12.5 spdh/spdh: embryonic day 12.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Regionally restricted 2_Gdf5 12.5 spdh/spdh No expression in phalangeal anlagen.

Specimen 2 Gdf5 13.5 wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 2_Gdf5 13.5 wt/wt Expression in developing joints of entire autopod.

Specimen 2 Gdf5 13.5 spdh/spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 2_Gdf5 13.5 spdh/spdh Some expression in joints between distal and middle phalanges, and between carpal bones. No expression in the joint interzone of digits.
TS21: forelimb digit 1 mesenchyme Present Regionally restricted 2_Gdf5 13.5 spdh/spdh Some expression in metacarpophalangeal joint of digit 1,


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/12/2021
MGI 6.17
The Jackson Laboratory