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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5423758
Gene symbol: Pycr2
Gene name: pyrroline-5-carboxylate reductase family, member 2
Probe: EH1140 probe 1059
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen EH1140; Specimen C2549: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_C2549_3_4A
TS22: central nervous system Strong Regionally restricted Embryo_C2549_3_4A
TS22: telencephalon Strong Regionally restricted Embryo_C2549_3_4A
TS22: cerebral cortex Moderate Regionally restricted Embryo_C2549_3_4A
TS22: neocortex Moderate Regionally restricted Embryo_C2549_3_4A
TS22: olfactory cortex Absent
TS22: main olfactory bulb Absent
TS22: piriform cortex Absent
TS22: hippocampus Absent
TS22: basal ganglia Strong Regionally restricted Embryo_C2549_3_4A
TS22: corpus striatum Moderate Regionally restricted Embryo_C2549_3_2A Expression was detected in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Absent
TS22: amygdala Absent
TS22: telencephalon septum Strong Regionally restricted Embryo_C2549_3_4A
TS22: pallidum Absent Expression was not detected in the pallidum (medial ganglionic eminence).
TS22: diencephalon Strong Regionally restricted Embryo_C2549_3_4A
TS22: thalamus Strong Regionally restricted Embryo_C2549_3_4A
TS22: hypothalamus Strong Regionally restricted Embryo_C2549_3_4A
TS22: midbrain Strong Regionally restricted Embryo_C2549_3_3C
TS22: pretectum Absent
TS22: superior colliculus Absent
TS22: inferior colliculus Absent
TS22: midbrain tegmentum Strong Regionally restricted Embryo_C2549_3_3C
TS22: hindbrain Moderate Regionally restricted Embryo_C2549_3_3C
TS22: cerebellum Absent
TS22: pons Moderate Regionally restricted Embryo_C2549_3_3C
TS22: medulla oblongata Moderate Regionally restricted Embryo_C2549_3_3C
TS22: spinal cord Moderate Regionally restricted Embryo_C2549_3_3C
TS22: choroid plexus Absent
TS22: meninges Absent
TS22: peripheral nervous system Absent
TS22: cranial ganglion Absent
TS22: dorsal root ganglion Absent
TS22: eye Moderate Regionally restricted Embryo_C2549_3_1B
TS22: retina Weak Regionally restricted Embryo_C2549_3_1D
TS22: lens Moderate Regionally restricted Embryo_C2549_3_1B
TS22: cornea Absent
TS22: optic nerve Absent
TS22: nose Absent
TS22: olfactory epithelium Absent
TS22: ear Strong Regionally restricted Embryo_C2549_3_3A
TS22: inner ear Strong Regionally restricted Embryo_C2549_3_3A
TS22: cochlea Strong Regionally restricted Embryo_C2549_3_3A
TS22: inner ear labyrinth Absent
TS22: middle ear Absent
TS22: alimentary system Moderate Regionally restricted Embryo_C2549_3_2A Expression was detected in the digestive system.
TS22: intestine Absent
TS22: salivary gland Weak Ubiquitous Embryo_C2549_3_2D
TS22: tongue Absent
TS22: tooth Weak Regionally restricted Embryo_C2549_3_4B
TS22: palatal shelf Absent
TS22: esophagus Absent
TS22: stomach Moderate Regionally restricted Embryo_C2549_3_2A
TS22: liver Weak Ubiquitous Embryo_C2549_3_2C
TS22: respiratory system Moderate Regionally restricted Embryo_C2549_3_2B
TS22: pharynx Absent
TS22: larynx Absent
TS22: trachea Weak Regionally restricted Embryo_C2549_3_4A
TS22: main bronchus Absent
TS22: lung Moderate Regionally restricted Embryo_C2549_3_2B
TS22: urinary system Weak Regionally restricted Embryo_C2549_3_3C Expression was weak in the genito-urinary system.
TS22: metanephros Weak Regionally restricted Embryo_C2549_3_3C
TS22: ureter Absent
TS22: bladder Absent
TS22: urethra Absent
TS22: reproductive system Absent
TS22: genital tubercle Absent
TS22: gonad Absent
TS22: gland Weak Regionally restricted Embryo_C2549_3_3D Expression was weak in the endocrine system.
TS22: thyroid gland Absent
TS22: pituitary gland Absent
TS22: pancreas Weak Ubiquitous Embryo_C2549_3_3D
TS22: adrenal gland Absent
TS22: cardiovascular system Strong Regionally restricted Embryo_C2549_3_3C
TS22: heart Strong Regionally restricted Embryo_C2549_3_3C
TS22: heart atrium Strong Regionally restricted Embryo_C2549_3_3C
TS22: heart ventricle Absent
TS22: blood vessel Absent
TS22: hemolymphoid system Absent Expression was not detected in the immune system.
TS22: spleen primordium Absent
TS22: thymus primordium Absent
TS22: appendicular skeleton Weak Regionally restricted Embryo_C2549_3_1C Expression was weak in the skeleton (limbs, shoulder, hip).
TS22: musculature Absent
TS22: face Absent Expression was not detected in the face/soft tissues.
TS22: facial bone primordium Strong Regionally restricted Embryo_C2549_3_4C
TS22: cranium Moderate Regionally restricted Embryo_C2549_3_1C Expression was detected in the skull (base and vault).
TS22: axial skeleton Moderate Regionally restricted Embryo_C2549_3_1C
TS22: tail Absent
TS22: forelimb Moderate Regionally restricted Embryo_C2549_3_1C
TS22: hindlimb Weak Regionally restricted Embryo_C2549_3_1D
TS22: integumental system Absent
TS22: skin Absent
TS22: hair Absent
TS22: vibrissa follicle Absent Expression was not detected in whisker follicle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory