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Gene Expression Data
Assay Details
Assay
Reference: J:86943 Lauren J, et al., Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci. 2003 Nov;24(3):581-94
Assay type: RNA in situ
MGI Accession ID: MGI:5316842
Gene symbol: Rtn4rl1
Gene name: reticulon 4 receptor-like 1
Probe: NGRL2 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Two different probes were used for in situ hybridisation experiments resulting in identical results. The authors did not specify which probe was used for the data shown; either this probe or NGRL2 cDNA2 (MGI:5316504).
Results
Specimen 4B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Strong 4B
TS21: inferior glossopharyngeal ganglion Strong 4B
TS21: inferior vagus ganglion Strong 4B
TS21: peripheral nervous system Strong 4B
TS21: trigeminal ganglion Strong 4B
TS21: vestibulo-cochlear ganglion Strong 4B
TS21: heart Present 4B
TS21: brain Weak Regionally restricted 4B
TS21: brainstem Weak Regionally restricted 4B
TS21: spinal cord Weak Regionally restricted 4B

Specimen 4F,G: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: spinal cord Present Regionally restricted 4F , 4G Expression is dorsal.
TS27: dorsal root ganglion Strong 4G , 4F
TS27: sympathetic ganglion Strong 4F , 4G

Specimen 5D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 5D
TS28: anterior olfactory nucleus Strong 5D
TS28: cortical layer II Strong 5D
TS28: cortical layer III Strong 5D
TS28: cortical layer IV Strong 5D
TS28: cortical layer V Strong 5D
TS28: cortical layer VI Strong 5D
TS28: habenula Strong 5D
TS28: hippocampal formation Strong 5D
TS28: main olfactory bulb mitral cell layer Strong 5D
TS28: midbrain Present 5D
TS28: thalamus Present 5D
TS28: brainstem Present Widespread 5D
TS28: choroid plexus Present 5D

Specimen 5E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong Regionally restricted 5E
TS28: cortical layer III Strong Regionally restricted 5E
TS28: cortical layer IV Strong Regionally restricted 5E
TS28: cortical layer V Strong Regionally restricted 5E
TS28: cortical layer VI Strong Regionally restricted 5E
TS28: caudate-putamen Present 5E
TS28: lateral septal nucleus Present 5E

Specimen 5F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 5F
TS28: cortical layer III Strong 5F
TS28: cortical layer IV Strong 5F
TS28: cortical layer V Strong 5F
TS28: cortical layer VI Strong 5F
TS28: hippocampal formation Strong 5F
TS28: amygdala Present 5F
TS28: medial habenular nucleus Present 5F
TS28: thalamus Present 5F

Specimen 6H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6H
TS28: cerebellum granule cell layer Present 6H

Specimen 6I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present 6I
TS28: cerebral cortex Present 6I
TS28: main olfactory bulb mitral cell layer Present 6I

Specimen 6J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Present 6J

Specimen 6K,L,M: postnatal adult (more )
Note: (K,L) Brightfield/dark field pair. (M) is a higher magnification of (L).
Structure Level Pattern Image Note
TS28: corpus callosum Present 6K , 6L , 6M Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer III Present 6K , 6L , 6M Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer IV Present 6K , 6L , 6M Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer V Present 6K , 6L , 6M Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer VI Present 6K , 6L , 6M Expression is in neurons, absent in oligodendrocytes.

Specimen 6N: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Strong 6N

Specimen Table 1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Strong
TS28: amygdala Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong
TS28: dentate gyrus granule cell layer Strong
TS28: dorsal root ganglion Strong
TS28: medial habenular nucleus Strong
TS28: piriform cortex Strong
TS28: trigeminal ganglion Strong
TS28: hippocampus CA2 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: hippocampus CA3 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: thalamus Strong Regionally restricted Expression is in the medial habenula and most other nuclei.
TS28: telencephalon Moderate Regionally restricted Expression is in periglomerular cells and the mitral cell layer and is absent in the internal granular layer.
TS28: brainstem Moderate Regionally restricted Expression is in the lateral lemniscus.
TS28: anterior olfactory nucleus Moderate
TS28: caudate-putamen Moderate
TS28: cerebellum Purkinje cell layer Moderate
TS28: cerebellum granule cell layer Moderate
TS28: choroid plexus Moderate
TS28: cuneate nucleus Moderate
TS28: inferior colliculus Moderate
TS28: inferior olivary nucleus Moderate
TS28: interpeduncular nucleus Moderate
TS28: lateral septal complex Moderate
TS28: nucleus of trapezoid body Moderate
TS28: red nucleus Moderate
TS28: septofimbrial nucleus Moderate
TS28: spinal cord dorsal horn Moderate
TS28: superior colliculus Moderate
TS28: trigeminal V mesencephalic nucleus Moderate
TS28: telencephalon septum Moderate Regionally restricted Expression is in the lateral septum, triangular septal nucleus, and septifimbrial nucleus.
TS28: cerebellum Weak Regionally restricted Expression is in lateral and medial cerebellar nuclei.
TS28: hypothalamus Moderate Regionally restricted Expression is in mamillary and premammillary nuclei.
TS28: cochlear nucleus Weak
TS28: gigantocellular reticular nucleus Weak
TS28: pontine nucleus Weak
TS28: spinal vestibular nucleus Weak
TS28: substantia nigra Weak
TS28: trigeminal V sensory nucleus Weak
TS28: arcuate nucleus Absent
TS28: globus pallidus Absent
TS28: locus coeruleus Absent
TS28: pallidum Absent
TS28: reticular tegmental nucleus Absent
TS28: spinal cord ventral horn Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory