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Gene Expression Data
Assay Details
Assay
Reference: J:166261 Brosel S, et al., Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease. Am J Pathol. 2010 Nov;177(5):2541-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4948532
Gene symbol: Sco1
Gene name: SCO1 cytochrome c oxidase assembly protein
Antibody: anti-Sco1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Assay notes: The immunohistochemical results were confirmed with additional antibodies raised against other epitopes in the protein.
Results
Specimen 5: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present Widespread 5_Sco1

Specimen Heart: postnatal (more )
Structure Level Pattern Image Note
TS28: heart Present S2_Sco1 Heart Staining is generally uniform in the "bulk" tissue.
TS28: heart blood vessel Strong S2_Sco1 Heart

Specimen Kidney: postnatal (more )
Structure Level Pattern Image Note
TS28: metanephros Present S2_Sco1 Kidney Staining is generally uniform in the "bulk" tissue.
TS28: renal vasculature Strong S2_Sco1 Kidney
TS28: glomerular capillary system Very strong S2_Sco1 Kidney The intense staining in the glomeruli is presumed to be in the capillaries.

Specimen Liver: postnatal (more )
Structure Level Pattern Image Note
TS28: liver Present S2_Sco1 Liver Staining is generally uniform in the "bulk" tissue.
TS28: liver sinusoid Strong S2_Sco1 Liver
TS28: liver vascular element Strong S2_Sco1 Liver
TS28: portal vein Strong S2_Sco1 Liver

Specimen Muscle: postnatal (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Weak S2_Sco1 Muscle Staining is generally uniform in the "bulk" tissue.
TS28: blood vessel Present S2_Sco1 Muscle


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory