About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:166261 Brosel S, et al., Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease. Am J Pathol. 2010 Nov;177(5):2541-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4948532
Gene symbol: Sco1
Gene name: SCO1 cytochrome c oxidase assembly protein
Antibody: anti-Sco1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Assay notes: The immunohistochemical results were confirmed with additional antibodies raised against other epitopes in the protein.
Results
Specimen 5: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present Widespread 5_Sco1
Specimen Heart: postnatal (more )
Structure Level Pattern Image Note
TS28: heart Present S2_Sco1 Heart Staining is generally uniform in the "bulk" tissue.
TS28: heart blood vessel Strong S2_Sco1 Heart
Specimen Kidney: postnatal (more )
Structure Level Pattern Image Note
TS28: metanephros Present S2_Sco1 Kidney Staining is generally uniform in the "bulk" tissue.
TS28: renal vasculature Strong S2_Sco1 Kidney
TS28: glomerular capillary system Very strong S2_Sco1 Kidney The intense staining in the glomeruli is presumed to be in the capillaries.
Specimen Liver: postnatal (more )
Structure Level Pattern Image Note
TS28: liver Present S2_Sco1 Liver Staining is generally uniform in the "bulk" tissue.
TS28: liver sinusoid Strong S2_Sco1 Liver
TS28: liver vascular element Strong S2_Sco1 Liver
TS28: portal vein Strong S2_Sco1 Liver
Specimen Muscle: postnatal (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Weak S2_Sco1 Muscle Staining is generally uniform in the "bulk" tissue.
TS28: blood vessel Present S2_Sco1 Muscle
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory