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Gene Expression Data
Assay Details
Assay
Reference: J:166965 Hawley SP, et al., Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan;240(1):221-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4946257
Gene symbol: Shc2
Gene name: SHC (Src homology 2 domain containing) transforming protein 2
Antibody: Anti-ShcB
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present 3_ShcB E12.5
TS20: heart Present 3_ShcB E12.5
TS20: embryo Present Widespread 3_ShcB E12.5 Robust expression was seen throughout many organs and structures in the E12.5 embryo.

Specimen 3 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis Present 3_ShcB E16.5
TS24: gut Present 3_ShcB E16.5
TS24: heart Present 3_ShcB E16.5
TS24: liver Present 3_ShcB E16.5
TS24: nucleus pulposus Present Regionally restricted 3_ShcB E16.5 Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.
TS24: skeleton Present Regionally restricted 3_ShcB E16.5 Expression was detected in populations of hypertrophic chondrocytes throughout the embryo.

Specimen 3 Liver: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: liver Present 3_ShcB Liver

Specimen 3 Gut: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: gut Present 3_ShcB Gut

Specimen 3 Bone: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nucleus pulposus Present Regionally restricted 3_ShcB Bone Expression was detected in the hypertrophic chondrocytes and chondrocyte-like cells contained within the nucleus pulposus in the central region of the intervertebral discs.

Specimen 3 Skin: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis Present 3_ShcB Skin

Specimen 3 Heart: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: heart Present 3_ShcB Heart


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory