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Gene Expression Data
Assay Details
Assay
Reference: J:157948 Jiang XS, et al., Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet. 2010 Apr 1;19(7):1347-57
Assay type: Western blot
MGI Accession ID: MGI:4836646
Gene symbol: Pak2
Gene name: p21 (RAC1) activated kinase 2
Antibody: Anti-Phospho-Pak1 (Thr423)/Pak2 (Thr402)
Detection system: Secondary antibody coupled to alkaline phosphatase
Assay notes: The antibody used in this assay recognizes the phosphorylated forms of both Pak1 and Pak2; both genes have been annotated.
Results Image: 2C P-Pak 1/2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Dhcr7 +/+ E18.5 TS26: brain Present involves: 129S4/SvJae Not Specified
Dhcr7 delta/delta E18.5 TS26: brain Strong (a) involves: 129S4/SvJae Dhcr7tm1Fdp/Dhcr7tm1FdpNot Specified
Notes:
(a) Expression level of the phosphorylated protein was significantly increased in the mutant compared with control brain tissue.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory