Ophn1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:85384 Fauchereau F, et al., The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain. Mol Cell Neurosci. 2003 Aug;23(4):574-86
Assay type:	RNA in situ
MGI Accession ID:	MGI:4430349
Gene symbol:	Ophn1
Gene name:	oligophrenin 1

Probe:	Ophn1 cDNA1
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

Specimen 1B: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image
TS24: embryo	Present	Ubiquitous	1B
TS24: brain	Strong		1B
TS24: spinal cord	Strong		1B
TS24: thymus	Strong		1B
TS24: lung	Present		1B
TS24: metanephros	Present		1B

Specimen 1D, 1E, 1F, 1G: postnatal adult (more

)
Note: (E, F, and G) are higher magnifications of the boxed areas in (D).

Structure	Level	Pattern	Image	Note
TS28: anterior olfactory nucleus	Present		1E , 1D
TS28: main olfactory bulb glomerular layer	Present		1E , 1D
TS28: main olfactory bulb mitral cell layer	Present		1E , 1D
TS28: olfactory tubercle	Present		1E , 1D
TS28: hippocampus CA2	Present	Regionally restricted	1D , 1F	Expression is in pyramidal cells.
TS28: hippocampus CA3	Present	Regionally restricted	1D , 1F	Expression is in pyramidal cells.
TS28: CA1 pyramidal cell layer	Present		1F , 1D
TS28: cerebral cortex	Present		1F , 1D
TS28: dentate gyrus granule cell layer	Present		1F , 1D
TS28: cerebellum Purkinje cell layer	Present		1D , 1G

Specimen Not shown, E10.5: embryonic day 10.5 (more

)

Specimen Not shown, E18.5: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: embryo	Present	Ubiquitous

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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