About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:151330 Bai XH, et al., ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor. Mol Cell Biol. 2009 Aug;29(15):4201-19
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4365941
Gene symbol: Adamts7
Gene name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
Antibody: anti-ADAMTS-7
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1Ca: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo mesenchyme Present Regionally restricted 1Ca Expression in proliferating mesenchymal cells.

Specimen 1Cb: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pre-cartilage condensation Present Regionally restricted 1Cb Expression clearly detectable in the center of a mesenchymal condensation and around it

Specimen 1Cc: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cartilage Strong Regionally restricted 1Cc Prominent expression in proliferating and prehypertrophic chondrocytes.

Specimen 1Cd: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cartilage Present Regionally restricted 1Cd Expression in proliferating and prehypertrophic chondrocytes in growth plates.

Specimen 1Ce: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: long bone epiphyseal plate Present Regionally restricted 1Ce Expression in proliferating and prehypertrophic chondrocytes in growth plates.

Specimen 1Cf: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate Present Regionally restricted 1Cf Expression throughout growth plate chondrocytes.

Specimen 7Cb/c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bone Present Regionally restricted 7Cc , 7Cb Expression in growth plate chondrocytes.

Specimen 7Ce/f: embryonic day 18.5; Pthlhtm1Hmk/Pthlhtm1Hmk (more )
Structure Level Pattern Image Note
TS26: bone Weak Regionally restricted 7Cf , 7Ce Expression in growth plate chondrocytes markedly reduced compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/19/2021
MGI 6.17
The Jackson Laboratory