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Gene Expression Data
Assay Details
Assay
Reference: J:143598 Jaks V, et al., Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet. 2008 Nov;40(11):1291-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3832644
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Reporter: GFP
Direct Detection
Results
Specimen S1d: embryonic day 18.5; Lgr5tm1(cre/ERT2)Cle/Lgr5tm1(cre/ERT2)Cle (more )
Note: S1f shows signal with overlay of nuclear stain.
Structure Level Pattern Image Note
TS26: vibrissa Present Regionally restricted S1f , S1d Authors report expression in the lower part of the outer root sheath and in the outer cell layer of the vibrissa bulb.
Specimen 1d: postnatal day 14; Lgr5tm1(cre/ERT2)Cle/Lgr5tm1(cre/ERT2)Cle (more )
Note: Anagen phase.
Structure Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 1d Expression localized to the lower part of the outer root sheath surrounding the hair follicle.
Specimen 1e: postnatal day 30; Lgr5tm1(cre/ERT2)Cle/Lgr5tm1(cre/ERT2)Cle (more )
Note: Catagen phase.
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1e Expressing cells link the mesenchymal component of the hair follicle (the dermal papilla) with the bulge area.
Specimen 1f: postnatal; Lgr5tm1(cre/ERT2)Cle/Lgr5tm1(cre/ERT2)Cle (more )
Note: Telogen phase.
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1f Expression concentrated in the lower bulge, and secondary germ.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory