Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:53687
Rau A, et al., Tectorin mRNA expression is spatially and temporally restricted during mouse inner ear development. J Comp Neurol. 1999 Mar 8;405(2):271-80
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:3789334
|
|
Gene symbol:
|
Tecta
|
|
Gene name:
|
tectorin alpha
|
|
Probe:
|
A1
|
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
|
Visualized with:
|
Autoradiography
|
|
|
Results
|
Specimen
Table 1--11.5:
embryonic day 11.5
(more  )
Specimen
Table 1--11.5:
(close  )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: saccule |
Absent |
|
|
There is no expression in the cochlea.
|
| TS19: vestibular component epithelium |
Absent |
|
|
In the vestibule there is no expression in the sensory epithelium nor in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
Specimen
Table 1--12.5:
embryonic day 12.5
(more )
Specimen
Table 1--12.5:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cochlea |
Moderate |
|
|
|
| TS20: vestibular component epithelium |
Moderate |
|
|
In the vestibule there is moderate expression in the sensory epithelium. There is no expression in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
Specimen
Table 1--13.5:
embryonic day 13.5
(more )
Specimen
Table 1--13.5:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlea |
Strong |
|
|
|
| TS21: vestibular component epithelium |
Strong |
|
|
In the vestibule there is strong expression in the sensory epithelium and in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
Specimen
Table 1--14.5:
embryonic day 14.5
(more )
Specimen
Table 1--14.5:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea |
Strong |
|
|
|
| TS22: inner ear vestibular component |
Strong |
|
|
In the vestibule there is strong expression in the sensory epithelium and in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
| TS22: vestibular component epithelium |
Strong |
|
|
In the vestibule there is strong expression in the sensory epithelium and in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
Specimen
Table 1--P1:
postnatal day 1
(more )
Specimen
Table 1--P1:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Strong |
|
|
|
| TS27: vestibular epithelium |
Present |
Non-Uniform |
|
In the vestibule there is moderate expression in the sensory epithelium and strong expression in the nonsensory epithelia surrounding transitional zones and the roof of the saccule.
|
Specimen
Table 1--P8:
postnatal day 8
(more )
Specimen
Table 1--P8:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Weak |
|
|
|
| TS28: utricle epithelium |
Present |
Non-Uniform |
|
In the utricle there is weak expression in the sensory epithelium and strong expression in the nonsensory epithelia.
|
Specimen
Table 1--P15:
postnatal day 15
(more )
Specimen
Table 1--P15:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1--P22:
postnatal day 22
(more )
Specimen
Table 1--P22:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 22
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1--P150:
postnatal day 150
(more )
Specimen
Table 1--P150:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 150
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: utricle epithelium |
Absent |
|
|
There is no expression in the sensory and nonsensory epithelia.
|
Specimen
2a:
embryonic day 12.5
(more )
Specimen
2a:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cochlear duct |
Present |
Regionally restricted |
2a
|
Expression is present at the basal end.
|
Specimen
2c:
embryonic day 13.5
(more )
Specimen
2c:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: cochlear duct |
Present |
Graded |
2c
|
Expression is present in the basal but not in the apical turn.
|
Specimen
2e:
embryonic day 14.5
(more )
Specimen
2e:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea |
Present |
Non-Uniform |
2e
|
Expression is present in the basal, middle, and apical profile. A broad band of expression encompasses most of the greater epithelial ridge and a narrow band is positioned where the lesser epithelial ridge begins to thin into a cuboidal epithelial layer.
|
Specimen
3a:
postnatal day 1
(more )
Specimen
3a:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Present |
Non-Uniform |
3a
|
A broad band of expression encompasses most of the greater epithelial ridge and a narrow band is positioned where the lesser epithelial ridge begins to thin into a cuboidal epithelial layer. Cells which will form interdental cells do not express.
|
Specimen
3c:
postnatal day 8
(more )
Specimen
3c:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
3c
|
Expression is no longer detected in the basal coil of the cochlea.
|
Specimen
4a:
embryonic day 14.5
(more )
Specimen
4a:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cochlea |
Present |
Non-Uniform |
4a
|
A broad band of expression encompasses most of the greater epithelial ridge and a narrow band is positioned where the lesser epithelial ridge begins to thin into a cuboidal epithelial layer.
|
Specimen
4c:
postnatal day 1
(more )
Specimen
4c:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Present |
Non-Uniform |
4c
|
A broad band of expression encompasses most of the greater epithelial ridge and a narrow band is positioned where the lesser epithelial ridge begins to thin into a cuboidal epithelial layer.
|
Specimen
4e:
postnatal day 8
(more )
Specimen
4e:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Absent |
|
4e
|
Expression is absent in all regions of the cochlea as the greater epithelial ridge recedes to form the internal sulcus.
|
Specimen
6a:
embryonic day 12.5
(more )
Specimen
6a:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
6b:
embryonic day 13.5
(more )
Specimen
6b:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: saccule epithelium |
Strong |
|
6b
|
Expression is present in cells forming the sensory epithelium as well as epithelium present in the roof of the organ.
|
| TS21: utricle epithelium |
Strong |
Regionally restricted |
6b
|
Expression is limited to cells forming the sensory epithelium.
|
Specimen
7a:
postnatal day 1
(more )
Specimen
7a:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: utricle epithelium |
Present |
Non-Uniform |
7a
|
Expression is mainly restricted to the cells of the surrounding transitional zone. Low levels of expression are detected in the sensory epithelium.
|
Specimen
Not shown:
postnatal day 22
(more )
Specimen
Not shown:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal day 22
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools