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Gene Expression Data
Assay Details
Assay
Reference: J:124184 Lai DM, et al., Angiopoietin-like protein 1 expression is related to intermuscular connective tissue and cartilage development. Dev Dyn. 2007 Sep;236(9):2643-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3722837
Gene symbol: Angptl1
Gene name: angiopoietin-like 1
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 9.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS15: head Present Regionally restricted 3A Expression is in the craniocervical junction.

Specimen 3B: embryonic day 11.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS19: branchial arch Present 3B
TS19: trunk somite Present 3B
TS19: limb Present Regionally restricted 3B Expression is in the major joints of the limb buds.

Specimen 3C: embryonic day 11.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS19: trunk somite Present Regionally restricted 3C Expression is in the newly formed somites.

Specimen 3D: embryonic day 11.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS19: trunk paraxial mesenchyme Present Regionally restricted 3D Expression is in the paraxial premuscle mass.
TS19: notochord Present 3D
TS19: body wall mesenchyme Present Regionally restricted 3D Expression is in the chest wall.
TS19: limb Present Regionally restricted 3D Expression is in the major joints of the limb buds.
TS19: heart Absent 3D

Specimen 3E: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: trunk Present Regionally restricted 3E Expression is in the trunk.
TS23: head Present Regionally restricted 3E Expression is in the face.
TS23: limb Present 3E
TS23: central nervous system Absent 3E
TS23: cranium Absent 3E

Specimen 4A: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: nucleus pulposus Present 4A
TS23: larynx Present Regionally restricted 4A Expression is in the perichondrium.
TS23: trachea cartilaginous ring Present Regionally restricted 4A Expression is in the perichondrium.
TS23: cardiovascular system Absent 4A

Specimen 4B: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: vertebra Present Regionally restricted 4B Expression is in the facet joint of the vertebrae.

Specimen 4C: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: trunk Present Regionally restricted 4C Expression is in the intermuscular connective tissue.
TS23: rib Present Regionally restricted 4C Expression is in the perichondrium.
TS23: cardiovascular system Absent 4C
TS23: heart Absent 4C

Specimen 4D: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: tongue Present Regionally restricted 4D Expression is in the intermuscular connective tissue of the tongue.

Specimen 4E: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: femur Present Regionally restricted 4E Expression is in the joint capsule.
TS23: hip joint primordium Present Regionally restricted 4E Expression is in the capsule.

Specimen 4F: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: nucleus pulposus Present 4F

Specimen 4G: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: diaphragm Present 4G

Specimen 4H: embryonic day 15.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS23: trunk mesenchyme Present Regionally restricted 4H Expression is in intermuscular connective tissue.
TS23: skeletal muscle Absent 4H Absent in the muscle in the trunk.

Specimen 5A: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: trachea Present Single cells 5A Expression is in some chondrocytes of the trachea.

Specimen 5B: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: rib Present Regionally restricted 5B Expression is in the perichondrium and intermuscular connective tissue.
TS28: musculature Absent 5B

Specimen 5C: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: rib Present Regionally restricted 5C Expression is in the costal perichondrium and fibrous insertion of the muscle around the rib in mesenchymal tissues.

Specimen 5D: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: rib Present Regionally restricted 5D Expression is in the costal perichondrium and fibrous insertion of the muscle around the rib in mesenchymal tissues.
TS28: musculature Absent 5D

Specimen 5E: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: blood vessel Absent 5E Absent in a representative vessel in the intermuscular connective tissue.

Specimen 5F: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: metanephros Absent 5F

Specimen 5G: postnatal month 6; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS28: brain Absent 5G

Specimen Not shown: postnatal day 0.5; Angptl1tm1Hung/Angptl1tm1Hung (more )
Structure Level Pattern Image Note
TS27: trachea cartilage Weak
TS27: trachea connective tissue Weak
TS27: trachea Weak Regionally restricted Expression is in intermuscular connective tissue.
TS27: limb Absent Absent in appendicular cartilage and joint capsules.
TS27: blood vessel Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory