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Gene Expression Data
Assay Details
Assay
Reference: J:64739 Wada R, et al., Microglial activation precedes acute neurodegeneration in sandhoff disease and is suppressed by bone marrow transplantation. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10954-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3581154
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: anti-F4/80 (Cl:A3-1)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen Sandhoff Disease: postnatal month 4; Hexbtm1Rlp/Hexbtm1Rlp (more )
Structure Level Pattern Image Note
TS28: spinal cord Strong Single cells 2a Expression is in amoeboid microglial cells.
Specimen Wild Type: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells 2b Expression is in ramified microglial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory