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Gene Expression Data
Assay Details
Assay
Reference: J:74049 Segat D, et al., Expression of matrilin-1, -2 and -3 in developing mouse limbs and heart. Matrix Biol. 2000 Dec;19(7):649-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3576359
Gene symbol: Matn1
Gene name: matrilin 1, cartilage matrix protein
Antibody: anti-matrilin 1
Detection system: Secondary antibody coupled to Cy3
Assay notes: The tissue was frozen, sectioned, and then fixed with 1% paraformaldehyde in PBS for 10 minutes.
Results
Specimen 1 9.5 dpc: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: cardiac muscle tissue Present 1_9.5 dpc Matn1
TS16: endocardial lining Weak 1_9.5 dpc Matn1

Specimen 1 10.5 dpc: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: heart Present 1_10.5 dpc Matn1

Specimen E14.5--not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: heart Present

Specimen 3 12.5 dpc: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: forelimb pre-cartilage condensation Present 3_12.5 dpc Matn1

Specimen E12.5--not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: vertebral cartilage condensation Present

Specimen 3 13.5 dpc: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: forelimb cartilage condensation Present 3_13.5 dpc Matn1

Specimen 3 14.5 dpc left: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: forelimb skeleton Present 3_14.5 dpc Matn1 left Expression is present in the cartilage.
TS23: hand mesenchyme Present Regionally restricted 3_14.5 dpc Matn1 left Expression is present in the tendon at its insertion into the third phalange.

Specimen 3 14.5 dpc right: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: forelimb skeleton Present 3_14.5 dpc Matn1 right Expression is present in the cartilage.

Specimen 4: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: humerus Present 4_Matn1 Expression is present in the elbow, in the zones of proliferating and early hypertrophic chondrocytes.
TS23: ulna Present 4_Matn1 Expression is present in the elbow, in the zones of proliferating and early hypertrophic chondrocytes.

Specimen 5 15.5 dpc: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: forelimb skeleton Present 5_15.5 dpc Matn1 Expression is present in cartilage of the developing bone anlage.
TS24: hand mesenchyme Present Regionally restricted 5_15.5 dpc Matn1 Expression is present in the ligaments and tendons about the carpus.
TS24: hand dermis Present 5_15.5 dpc Matn1

Specimen 5 17.5 dpc left: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb skeleton Present 5_17.5 dpc Matn1 left Expression is present in cartilage of the developing bone anlage.
TS26: hand mesenchyme Present Regionally restricted 5_17.5 dpc Matn1 left Expression is present in the ligaments and tendons about the carpus.
TS26: hand dermis Present 5_17.5 dpc Matn1 left

Specimen 5 17.5 dpc right: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb skeleton Present 5_17.5 dpc Matn1 right Expression is present in cartilage of the developing bone anlage.
TS26: hand mesenchyme Present 5_17.5 dpc Matn1 right Expression is present in the ligaments and tendons about the carpus.
TS26: hand dermis Present 5_17.5 dpc Matn1 right

Specimen 6: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: humerus Present Non-Uniform 6_Matn1 Expression is not as intensive at the articular surface as it is in the deeper zone of proliferating cells.
TS24: ulna Present Non-Uniform 6_Matn1 Expression is not as intensive at the articular surface as it is in the deeper zone of proliferating cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory