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Gene Expression Data
Assay Details
Assay
Reference: J:95365 Kim MH, et al., Mph2 expression in germinal zones of the mouse brain. Dev Dyn. 2005 Jan;232(1):209-15
Assay type: RNA in situ
MGI Accession ID: MGI:3573940
Gene symbol: Phc2
Gene name: polyhomeotic 2
Probe: IMAGE clone 1297376
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon lateral wall ventricular layer Present 2A
TS19: telencephalon ventricular layer Present 2A

Specimen 2B,C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 2C , 2B Expression is in germinal zones; the cortical ventricular zone and the ganglionic eminences.
TS21: ganglionic eminence Present 2C , 2B
TS21: cortical plate Present 2B , 2C Lower levels in the cortical plate.

Specimen 2D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Present Regionally restricted 2D Expression is in the proliferating regions of the forebrain in addition to the dorsal thalamus, cortical plate, the emerging habenular nucleus and the cortical hem of the developing hippocampus.
TS23: cortical plate Present 2D

Specimen 2E,F,G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon Present Regionally restricted 2F , 2G , 2E Expression is in the cortical ventricular zone, cortical plate, and ganglionic eminences and in lower levels in the intermediate zone and marginal zone.
TS25: cortical plate Present 2G , 2E , 2F
TS25: ganglionic eminence Present 2G , 2E , 2F
TS25: cerebral cortex intermediate zone Weak 2E , 2G , 2F

Specimen 2H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Present Regionally restricted 2H Expression is in the anterior arm of the subventricular zone extending into the olfactory bulbs.
TS25: olfactory lobe Present Regionally restricted 2H Expression is in the anterior arm of the subventricular zone extending into the olfactory bulbs.
TS25: midbrain Absent 2H

Specimen Not Shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Present Regionally restricted Expression is in the external granule layer.

Specimen 3A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: brain subventricular zone Very strong Regionally restricted 3A Expression is in the anterior part of subventricular zone.
TS27: hippocampus Present 3A
TS27: rostral migratory stream Present 3A
TS27: neocortex Weak 3A

Specimen 3B,C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb Very strong 3B , 3C
TS27: brain subventricular zone Very strong Regionally restricted 3B , 3C Expression is dorsal and lateral.

Specimen 3D: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: brain subventricular zone Present Regionally restricted 3D Expression is in the anterior part of subventricular zone.
TS27: main olfactory bulb Present Regionally restricted 3D

Specimen 3E: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: brain subventricular zone Present 3E
TS28: main olfactory bulb Present 3E

Specimen 3F: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 3F
TS28: brain subventricular zone Present Regionally restricted 3F Expression is in the dorso-lateral wall.

Specimen 3G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 3G
TS28: main olfactory bulb granule cell layer Present 3G
TS28: brain subventricular zone Present Regionally restricted 3G Expression is in the anterior part of subventricular zone.

Specimen 4A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Very strong 4A

Specimen 4B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Very strong 4B

Specimen 4C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 4C
TS27: cerebellum external granule cell layer Present 4C
TS27: cerebellum molecular layer Present Single cells 4C Expressing cells migrate through the molecular layer.

Specimen 4D: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 4D
TS27: cerebellum external granule cell layer Present 4D
TS27: cerebellum molecular layer Present Single cells 4D Expressing cells migrate through the molecular layer.

Specimen 4E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4E
TS28: cerebellum external granule cell layer Present 4E
TS28: cerebellum internal granule cell layer Present 4E
TS28: cerebellum molecular layer Present Single cells 4E Expressing cells migrate through the molecular layer.

Specimen 4F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4F
TS28: cerebellum external granule cell layer Present 4F
TS28: cerebellum internal granule cell layer Present 4F
TS28: cerebellum molecular layer Present Single cells 4F Expressing cells migrate through the molecular layer.

Specimen 4G: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Very strong 4G
TS28: cerebellum Purkinje cell layer Present 4G

Specimen 4H: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Very strong 4H
TS28: cerebellum Purkinje cell layer Present 4H

Specimen 4I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Very strong 4I
TS28: cerebellum Purkinje cell layer Present 4I

Specimen 4J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Very strong 4J
TS28: cerebellum Purkinje cell layer Present 4J

Specimen 5A,B,C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 5B , 5C , 5A
TS28: main olfactory bulb granule cell layer Present 5B , 5C , 5A
TS28: rostral migratory stream Weak Single cells 5C , 5B , 5A Staining in the horizontal limb of the rostral migratory stream.

Specimen 5D,E,F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Very strong 5E , 5F , 5D
TS28: hippocampus CA3 Very strong 5E , 5F , 5D
TS28: dentate gyrus granule cell layer Very strong Regionally restricted 5F , 5D , 5E Expression is in the outer shell.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory