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Gene Expression Data
Assay Details
Assay
Reference: J:67268 Rezgaoui M, et al., Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain. Mech Dev. 2001 Feb;100(2):335-8
Assay type: RNA in situ
MGI Accession ID: MGI:2677010
Gene symbol: Sorcs2
Gene name: sortilin-related VPS10 domain containing receptor 2
Probe: Sorcs2 cDNA3
Probe preparation: Antisense RNA labelled with S35
Assay notes: Identical results were obtained using probe Sorcs2 cDNA4 (MGI:2677006), containing nucleotides 2580-4038 of AY004316. The authors did not specify which probe was used in the pictured assay.
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung epithelium Strong 2A
TS19: neural tube floor plate Strong 2A
TS19: midbrain floor plate Strong 2A
TS19: myelencephalon floor plate Strong 2A
TS19: heart Present 2A
TS19: pre-cartilage condensation Present 2A
TS19: somite Present 2A
TS19: embryo Present Regionally restricted 2A Expression is in connective tissue.

Specimen 2B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Strong 2B
TS22: medulla oblongata floor plate Strong 2B
TS22: midbrain floor plate Strong 2B
TS22: hindbrain Strong Regionally restricted 2B Expression is in the floor plate.
TS22: cartilage Present 2B
TS22: skeletal muscle Present 2B
TS22: embryo Present Regionally restricted 2B Expression is in connective tissue.
TS22: heart Weak 2B

Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cartilage Present 2C
TS24: lung epithelium Present 2C
TS24: thalamus Present 2C
TS24: embryo Present Regionally restricted 2C Expression is in connective tissue.
TS24: skeletal muscle Weak 2C
TS24: smooth muscle tissue Weak 2C

Specimen 2D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Weak Regionally restricted 2D Expression is in the ventral region extending to the ventral horns.
TS17: neural tube floor plate Strong 2D

Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube floor plate Strong 2E
TS19: future spinal cord Present Regionally restricted 2E Expression is in the ventral spinal cord extending dorsally.

Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord floor plate Strong 2F

Specimen 2G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord floor plate Weak 2G
TS22: spinal cord Present Regionally restricted 2G Expression is in the ventral spinal cord extending dorsally.

Specimen 2H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: myelencephalon floor plate Strong 2H

Specimen 2I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medulla oblongata floor plate Strong 2I

Specimen 2J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medulla oblongata floor plate Present 2J
TS22: medulla oblongata basal plate ventricular layer Present 2J

Specimen 2K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2K Expression is in the dopaminergic region.
TS19: diencephalon Present Regionally restricted 2K Expression is in the thalamus.
TS19: diencephalon lateral wall marginal layer Present 2K
TS19: telencephalon marginal layer Present 2K

Specimen 2L: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thalamus Present 2L
TS24: cerebral cortex ventricular layer Present 2L
TS24: diencephalon lateral wall ventricular layer Present 2L

Specimen 2M: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Present Regionally restricted 2M Strong signals over the ependymal layer and weak signals over the substantia nigra.

Specimen 2N: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thalamus Present Regionally restricted 2N Expression is in the mediodorsal thalamic nuclei.

Specimen 2O: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thalamus Present Regionally restricted 2O Expression is in the mediodorsal thalamic nuclei.

Specimen 3A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: head mesenchyme Present Regionally restricted 3A Expression is in facial mesenchyme.
TS24: olfactory epithelium Present 3A

Specimen 3B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cardiac muscle tissue Present 3B
TS24: lung epithelium Strong 3B
TS24: axial skeleton Present Regionally restricted 3B Expression is in vertebra.
TS24: skeletal muscle Present 3B

Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted The authors state that this gene was differentially expressed in the adult brain, but did not provide details.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory