t<Tu1> Spontaneous Allele Detail MGI Mouse (MGI:1856770)

t^Tu1
Spontaneous Allele Detail

Summary

Symbol:	t^Tu1
Name:	t-complex; t, Tubingen 1
MGI ID:	MGI:1856770
Gene:	t Location: unknown Genetic Position: Chr17, Syntenic
Alliance:	t^Tu1 page

Mutation
origin

Strain of Origin:

STOCK + t^w12 Itpr3^tf H2^w30/Rb(16.17)7Bnr + + H2^d x + + + H2^b/+ + + H2^b

Mutation
description

Allele Type:		Spontaneous
Inheritance:		Recessive

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any t Mutation:	19 strains or lines available

Notes

Robertsonian Rb7 is Rb(16.17)Bnr. t^Tu1 originated with a crossing-over event between the centromere and the H-2 complex producing an exceptional male having a normal tail and lacking Rb7, but carrying H-2^d, suggesting that one Chr 17 comprised the centromeric portion of the t^w12 haplotype and the telomeric portion of the Rb17 chromosome.

References

Original:	J:6700 Styrna J, et al., Evidence for two regions in the mouse t complex controlling transmission ratios. Genet Res. 1981 Dec;38(3):315-25
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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