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Pbx2em1Ucph
Endonuclease-mediated Allele Detail
Summary
Symbol: Pbx2em1Ucph
Name: pre B cell leukemia homeobox 2; endonuclease-mediated mutation 1, University of Copenhagen
MGI ID: MGI:6761310
Gene: Pbx2  Location: Chr17:34811233-34816374 bp, + strand  Genetic Position: Chr17, 18.17 cM
Alliance: Pbx2em1Ucph page
Mutation
origin
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Insertion
    CRISPR-targeting inserted a floxed CMV hygromycin polyadenylation cassette into exon 1. (J:310041)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pbx2 Mutation:  14 strains or lines available
References
Original:  J:310041 Mariani L, et al., A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm. Nat Commun. 2021 Aug 26;12(1):5136
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory