Esr2tm1.1Roli
Targeted Allele Detail
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| Symbol: |
Esr2tm1.1Roli |
| Name: |
estrogen receptor 2 (beta); targeted mutation 1.1, Rong Li |
| MGI ID: |
MGI:6729890 |
| Synonyms: |
Esr2Y55F |
| Gene: |
Esr2 Location: Chr12:76167193-76224033 bp, - strand Genetic Position: Chr12, 33.52 cM, cytoband D1-D3
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| Alliance: |
Esr2tm1.1Roli page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:308292
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6
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| Allele Type: |
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Targeted (Not Specified) |
| Mutation: |
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Single point mutation
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Mutation details: An A-to-T change resulting in a tyrosine to phenylalanine substitution at amino acid 55 (p.Y55F) was introduced in exon 1 and an FRT-flanked neomycin selection cassette was inserted downstream of exon 1. Flp-mediated recombination removed the selection cassette.
(J:308292)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Esr2 Mutation: |
32 strains or lines available
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| Original: |
J:308292 Yuan B, et al., Estrogen receptor beta signaling in CD8(+) T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch. J Immunother Cancer. 2021 Jan;9(1) |
| All: |
2 reference(s) |
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Analysis Tools
