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Taf1em2Ems
Endonuclease-mediated Allele Detail
Summary
Symbol: Taf1em2Ems
Name: TATA-box binding protein associated factor 1; endonuclease-mediated mutation 2, Elizabeth M Simpson
MGI ID: MGI:6728059
Synonyms: Taf1fl
Gene: Taf1  Location: ChrX:100576335-100644635 bp, + strand  Genetic Position: ChrX, 44.29 cM
Alliance: Taf1em2Ems page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCRISPR/cas9 genome editing is used to insert loxP sites flanking exon 8 (with respect to transcripts Taf1-202 or -206) or exons 8-9 (with respect to transcript Taf1-201). Approximately 55 kb spanning the loxP sites was sequenced.
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Taf1 Mutation:  10 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory