About   Help   FAQ
Mlxipltm1.1Mws
Targeted Allele Detail
Summary
Symbol: Mlxipltm1.1Mws
Name: MLX interacting protein-like; targeted mutation 1.1, Mark W Sleeman
MGI ID: MGI:6694840
Synonyms: ChREBP fl
Gene: Mlxipl  Location: Chr5:135118744-135167236 bp, + strand  Genetic Position: Chr5, 75.0 cM
Alliance: Mlxipltm1.1Mws page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:263597
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsExon 1 was flanked by loxP sites. An frt-flanked neomycin selection cassette was removed via FLP1-mediated recombination, (J:263597)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mlxipl Mutation:  54 strains or lines available
References
Original:  J:263597 Jois T, et al., Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice. Mol Metab. 2017 Nov;6(11):1381-1394
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory