Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Sall1em1(Ncre)Jung
Name:	spalt like transcription factor 1; endonuclease-mediated mutation 1, Steffen Jung
MGI ID:	MGI:6508988
Synonyms:	Sall1ncre
Gene:	Sall1  Location: Chr8:89753867-89770790 bp, - strand  Genetic Position: Chr8, 43.51 cM, cytoband D
Alliance:	Sall1em1(Ncre)Jung page

Strain of Origin:

C57BL/6JOlaHsd

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Sall1em1(Ncre)Jung expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sall1 (MGI:1889585)   Mutation details: CRISPR/Cas9 system inserted a cassette encoding a viral 2A oligopeptide (T2A) self-cleaving peptide, that mediates ribosomal skipping, fused to an N-terminal Cre recombinase fragment (NCre), directly downstream of the spalt like transcription factor 1 (Sall1) gene. (J:302588)

Activity:	Tissue activity of this recombinase allele
Driver:	Sall1 (mouse) Summary of all recombinase alleles driven by Sall1. Comparative matrix view of recombinase activities Alliance mouse Sall1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sall1 Mutation:	77 strains or lines available

Original:	J:302588 Kim JS, et al., A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages. Immunity. 2021 Jan 12;54(1):176-190.e7
All:	2 reference(s)