Atf3tm2.1Kitab
Targeted Allele Detail
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| Symbol: |
Atf3tm2.1Kitab |
| Name: |
activating transcription factor 3; targeted mutation 2.1, Shigetaka Kitajima |
| MGI ID: |
MGI:6502676 |
| Synonyms: |
Atf3f |
| Gene: |
Atf3 Location: Chr1:190902493-190915530 bp, - strand Genetic Position: Chr1, 96.28 cM, cytoband H6
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| Alliance: |
Atf3tm2.1Kitab page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:228274
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| Parent Cell Line: |
RW-4 (ES Cell)
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| Strain of Origin: |
129X1/SvJ
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted into intron 1 and a loxP site flanked neomycin resistance gene cassette into intron 2 2. The neo cassette was removed through subsequent cre-mediated recombination, leaving a conditional-ready allele with exon 2 floxed.
(J:228274)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Atf3 Mutation: |
19 strains or lines available
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| Original: |
J:228274 Taketani K, et al., Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells. Oncogene. 2012 Apr 26;31(17):2210-21 |
| All: |
2 reference(s) |
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Analysis Tools
