Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tph1em1Cya
Name:	tryptophan hydroxylase 1; endonuclease-mediated mutation 1, Cyagen Biosciences
MGI ID:	MGI:6489929
Synonyms:	Tph1em1Cgen, Tph1em1cyagen
Gene:	Tph1  Location: Chr7:46294065-46321961 bp, - strand  Genetic Position: Chr7, 30.43 cM
Alliance:	Tph1em1Cya page

Strain of Origin:

C57BL/6N

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion     Exons 3 to 10 were selected as the target site. (J:296241)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tph1 Mutation:	39 strains or lines available

Original:	J:296241 Nonogaki K, et al., Whey protein isolate inhibits hepatic FGF21 production, which precedes weight gain, hyperinsulinemia and hyperglycemia in mice fed a high-fat diet. Sci Rep. 2020 Sep 25;10(1):15784
All:	1 reference(s)