Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Npas2MSN/GammMmmh
Name:	neuronal PAS domain protein 2; MSN/GammMmmh
MGI ID:	MGI:6471778
Synonyms:	Npas2L481P
Gene:	Npas2  Location: Chr1:39233013-39402321 bp, + strand  Genetic Position: Chr1, 17.98 cM
Alliance:	Npas2MSN/GammMmmh page

Strain of Origin:

MSN/GammMmmh

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: This allele contains the following spontaneous mutation(s) that have a predicted consequential effect on the encoded peptide and that are specific to (fixed in) the MSN (Madison) strain used as a mania model, as compared to: the Hsd:ICR strain from which it is derived; the MaD2 (Maternal Defense 2) strain, which is also derived from Hsd:ICR but wasn't selected for mania; the C57BL/6J reference strain. Build GRCm38 genomic coordinates: g.chr1:39336044T>C (p.L481P). (J:267654)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npas2 Mutation:	45 strains or lines available

Original:	J:267654 Saul MC, et al., Genomic variants in an inbred mouse model predict mania-like behaviors. PLoS One. 2018;13(5):e0197624
All:	1 reference(s)