Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Nfe2l2em1Smoc
Name:	nuclear factor, erythroid derived 2, like 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6430635
Synonyms:	Nrf2-
Gene:	Nfe2l2  Location: Chr2:75505857-75534985 bp, - strand  Genetic Position: Chr2, 44.75 cM
Alliance:	Nfe2l2em1Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion     CRISPR/Cas9 genome editing technology was used to delete exons 2-5 of the gene. (J:238766)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nfe2l2 Mutation:	88 strains or lines available

Original:	J:258328 Sun W, et al., miR-181c protects CsA-induced renal damage and fibrosis through inhibiting EMT. FEBS Lett. 2017 Nov;591(21):3588-3599
All:	2 reference(s)