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Apoa1em1.1Arem
Endonuclease-mediated Allele Detail
Summary
Symbol: Apoa1em1.1Arem
Name: apolipoprotein A-I; endonuclease-mediated mutation 1.1, Alan Remaley
MGI ID: MGI:6423713
Gene: Apoa1  Location: Chr9:46139928-46141767 bp, + strand  Genetic Position: Chr9, 25.36 cM, cytoband A2-A4
Alliance: Apoa1em1.1Arem page
Mutation
origin
Strain of Origin:  (C57BL/6 x DBA/2J)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe floxed Apoa1 strain was created by using CRISPR-Cas9 technology. The strain was first created with LoxP site inserted into Intron 1, then the strain was used for insertion of a second LoxP site into Intron 3 of mouse Apoa1 gene. (J:94077)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apoa1 Mutation:  16 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory