Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Nkx2-1tm1Ikono
Name:	NK2 homeobox 1; targeted mutation 1, Laertis Ikonomou
MGI ID:	MGI:6423594
Synonyms:	Nkx2-1GFP
Gene:	Nkx2-1  Location: Chr12:56578741-56583570 bp, - strand  Genetic Position: Chr12, 24.42 cM, cytoband C1-C3
Alliance:	Nkx2-1tm1Ikono page

Germline Transmission:	Earliest citation of germline transmission: J:287785
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: The GFP reporter replaced the second ATG start site through the end of the Nkx2-1 homeobox (positions 7957-9480 in GenBank locus MMU19755). The puromycin cassette was excised by transient cre exposure. (J:287785)

In Mice Carrying this Mutation:

149 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nkx2-1 Mutation:	24 strains or lines available

Original:	J:287785 Longmire TA, et al., Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012 Apr 6;10(4):398-411
All:	7 reference(s)