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Mlxipltm1.1Wpjz
Targeted Allele Detail
Summary
Symbol: Mlxipltm1.1Wpjz
Name: MLX interacting protein-like; targeted mutation 1.1, Weiping Zhang
MGI ID: MGI:6423078
Synonyms: ChREBPflox
Gene: Mlxipl  Location: Chr5:135118744-135167236 bp, + strand  Genetic Position: Chr5, 75.0 cM
Alliance: Mlxipltm1.1Wpjz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:286982
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe eighth exon of the gene was flanked with the LoxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was subsequently removed via FLP-mediated recombination in the germline. (J:286982)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mlxipl Mutation:  54 strains or lines available
References
Original:  J:286982 Shi JH, et al., Liver ChREBP Protects Against Fructose-Induced Glycogenic Hepatotoxicity by Regulating L-Type Pyruvate Kinase. Diabetes. 2020 Apr;69(4):591-602
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory