Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il4tm1.1Wep
Name:	interleukin 4; targeted mutation 1.1, William E Paul
MGI ID:	MGI:2388164
Synonyms:	G4, GFP/IL4, Il4eGFP, Il4G4, IL-4/GFP
Gene:	Il4  Location: Chr11:53503287-53509492 bp, - strand  Genetic Position: Chr11, 31.97 cM
Alliance:	Il4tm1.1Wep page

Germline Transmission:	Earliest citation of germline transmission: J:67964
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: This allele is a derivative of Il4tm1Wep. The floxed neo cassette was removed by mating mutant animals to a transgenic line expressing cre recombinase in the oocytes, leaving behind a loxP site and the GFP knock-in cassette in place of exon 1. (J:67964)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:	42 strains or lines available

Original:	J:67964 Hu-Li J, et al., Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 2001 Jan;14(1):1-11
All:	25 reference(s)