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Nr1d1tm1Laz
Targeted Allele Detail
Summary
Symbol: Nr1d1tm1Laz
Name: nuclear receptor subfamily 1, group D, member 1; targeted mutation 1, Mitchell A Lazar
MGI ID: MGI:6363013
Synonyms: Nr1d1tm1Geno, Rev-erbalphafl
Gene: Nr1d1  Location: Chr11:98658758-98666159 bp, - strand  Genetic Position: Chr11, 62.66 cM
Alliance: Nr1d1tm1Laz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:279241
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe DNA-binding domain-containing exons 3-5 are flanked by loxP sites. An FRT-lanked neomycin resistance cassette is present. (J:279241)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr1d1 Mutation:  40 strains or lines available
References
Original:  J:279241 Dierickx P, et al., SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12147-12152
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory