Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Riox2tm1Itl
Name:	ribosomal oxygenase 2; targeted mutation 1, Ingenious Targeting Laboratory
MGI ID:	MGI:6356818
Synonyms:	mdig-
Gene:	Riox2  Location: Chr16:59292138-59312824 bp, + strand  Genetic Position: Chr16, 34.83 cM
Alliance:	Riox2tm1Itl page

Germline Transmission:	Earliest citation of germline transmission: J:278267
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The region from exon 2 to exon 8 of the gene was replaced by a neomycin selection cassette. (J:278267)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Riox2 Mutation:	23 strains or lines available

Original:	J:278267 Thakur C, et al., Oncoprotein mdig contributes to silica-induced pulmonary fibrosis by altering balance between Th17 and Treg T cells. Oncotarget. 2015 Feb 28;6(6):3722-36
All:	1 reference(s)