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Transgene Detail
Symbol: Tg(Elf5-cre/ERT2,-GFP)3Rcha
Name: transgene insertion 3, Rumela Chakrabarti
MGI ID: MGI:6343503
Synonyms: Elf5CreERT2-GFP
Transgene: Tg(Elf5-cre/ERT2,-GFP)3Rcha  Location: unknown  
Strain of Origin:  Not Specified
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
Mutation detailsA partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 3 show weak GPF and exluded from further analyses. (J:277468)
 Tissue activity of this recombinase allele
Driver: Elf5     Summary of all recombinase alleles driven by Elf5. Comparative matrix view of recombinase activities

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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:277468 Singh S, et al., A new Elf5(Cre) (ERT) (2-) (GFP) BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues. FEBS Lett. 2019 May;593(10):1030-1039
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory