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Ddx3xem2Osb
Endonuclease-mediated Allele Detail
Summary
Symbol: Ddx3xem2Osb
Name: DEAD box helicase 3, X-linked; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:6323448
Synonyms: XDdx3x-em2
Gene: Ddx3x  Location: ChrX:13147261-13160222 bp, + strand  Genetic Position: ChrX, 8.17 cM
Alliance: Ddx3xem2Osb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:274336
Parent Cell Line:  EGR-G01 (ES Cell)
Strain of Origin:  (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
    CRISPR/Cas9 mutagenesis introduced a 29-bp deletion in the gene. (J:274336)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddx3x Mutation:  6 strains or lines available
References
Original:  J:274336 Matsumura T, et al., An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility. J Reprod Dev. 2019 Apr 12;65(2):121-128
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory