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Tg(Hspa1a-Sry)40Yokan
Transgene Detail
Summary
Symbol: Tg(Hspa1a-Sry)40Yokan
Name: transgene insertion 40, Yoshiakira Kanai
MGI ID: MGI:6306632
Synonyms: HSP-Sry
Transgene: Tg(Hspa1a-Sry)40Yokan  Location: unknown  
Alliance: Tg(Hspa1a-Sry)40Yokan page
Transgene
origin
Strain of Origin:  C57BL/6NCrSlc
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA mouse genomic clone was constructed in which the the entire 5-flanking region of the murine Sry gene was replaced with the mouse Hspa1a promoter sequences. Two sex-reversal mouse lines were generated (40 and 46) but only 40 was studied further due to lethality associated with line 46. (J:96334)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:96334 Kidokoro T, et al., Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry expression during early phases of testis differentiation in mice. Dev Biol. 2005 Feb 15;278(2):511-25
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory