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Cdx2tm1.1Shiv
Targeted Allele Detail
Summary
Symbol: Cdx2tm1.1Shiv
Name: caudal type homeobox 2; targeted mutation 1.1, Ramesh Shivdasani
MGI ID: MGI:6306312
Gene: Cdx2  Location: Chr5:147237710-147244059 bp, - strand  Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
Alliance: Cdx2tm1.1Shiv page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:273411
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Inversion
 
Mutation detailsLoxP sites were placed flanking exon 2 of mouse Cdx2 in a targeting construct containing an FRT-flanked Neomycin resistance (NeoR) cassette immediately downstream of the 3 LoxP site. Chimeric progeny were crossed with Flp-expressing mice to excise the NeoR gene. (J:273411)
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdx2 Mutation:  22 strains or lines available
References
Original:  J:273411 Verzi MP, et al., Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell. 2010 Nov 16;19(5):713-26
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory