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Sryem6Jae
Endonuclease-mediated Allele Detail
Summary
Symbol: Sryem6Jae
Name: sex determining region of Chr Y; endonuclease-mediated mutation 6, Rudolf Jaenisch
MGI ID: MGI:6294053
Synonyms: Sry-GFP
Gene: Sry  Location: ChrY:2662471-2663658 bp, - strand  Genetic Position: ChrY, cytoband p
Alliance: Sryem6Jae page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:273412
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Reporter)
Mutation:    Insertion
 
Mutation detailsTALEN-targeting of the translation start site introduced a GFP reporter gene and floxed puromycin resistance cassette. (J:273412)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sry Mutation:  51 strains or lines available
References
Original:  J:273412 Wang H, et al., TALEN-mediated editing of the mouse Y chromosome. Nat Biotechnol. 2013 Jun;31(6):530-2
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory