Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Bach2M1Btlr
Name:	BTB and CNC homology, basic leucine zipper transcription factor 2; mutation 1, Bruce Beutler
MGI ID:	MGI:6283665
Synonyms:	Magnificat
Gene:	Bach2  Location: Chr4:32238804-32586108 bp, + strand  Genetic Position: Chr4, 14.02 cM, cytoband A4
Alliance:	Bach2M1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced A to T transversion at base pair 32,563,324 (v38) on chromosome 4, or base pair 324,751 in the GenBank genomic region NC_000070. The mutation corresponds to residue 1,951 in the mRNA sequence NM_001109661 within exon 3 of 5 total exons. The mutation results in a glutamic acid to valine substitution at position 597 (E597V) in the BACH2 protein. (J:272023) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bach2 Mutation:	44 strains or lines available

Original:	J:272023 Zhong X, et al., Mutagenetix entry for Magnificat. MGI Direct Data Submission. 2019;
All:	1 reference(s)