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Ctcfltm1.1Gal
Targeted Allele Detail
Summary
Symbol: Ctcfltm1.1Gal
Name: CCCTC-binding factor like; targeted mutation 1.1, Niels Galjart
MGI ID: MGI:6281588
Synonyms: Ctcfldel
Gene: Ctcfl  Location: Chr2:172935402-172961318 bp, - strand  Genetic Position: Chr2, 95.74 cM
Alliance: Ctcfltm1.1Gal page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:269332
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA GFP reporter gene fused was inserted inframe at the translation start site and followed by a floxed neomycin resistance cassette. A floxed puromycin resistance cassette was inserted downstream of exon 8. Cre-mediated recombination removed the remainder of exon 1 through exon 8. (J:269332)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctcfl Mutation:  34 strains or lines available
References
Original:  J:269332 Sleutels F, et al., The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin. 2012 Jun 18;5(1):8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory