Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pcbd2em1Kng
Name:	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2; endonuclease-mediated mutation 1, David M Kingsley
MGI ID:	MGI:6281579
Synonyms:	Pitx1PelB
Gene:	Pcbd2  Location: Chr13:55875181-55924643 bp, + strand  Genetic Position: Chr13, 30.06 cM, cytoband B2
Alliance:	Pcbd2em1Kng page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Not Specified) Mutation:    Deletion   Pcbd2em1Kng involves 1 genes/genome features (Pitx1) View all   Mutation details: CRISPR/Cas9 methodology was used to delete a 9425bp PelB (pelvic limb enhancer B) region corresponding to mm9 Chr13:55,850,296-55,859,733 within a large intron (intron 2) of the gene. (J:271427)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pcbd2 Mutation:	12 strains or lines available

Original:	J:271427 Thompson AC, et al., A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates. Elife. 2018 Nov 30;7:e38555
All:	1 reference(s)