Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Pck1-SREBF1_ic)1Reh
Name:	transgene insertion 1, Robert E Hammer
MGI ID:	MGI:6275990
Transgene:	Tg(Pck1-SREBF1_ic)1Reh  Location: unknown
Alliance:	Tg(Pck1-SREBF1_ic)1Reh page

Strain of Origin:

(C57BL/6J x SJL)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: This transgene encodes amino acids 1436 of human SREBP-1c isoform under the control of the rat PEPCK promoter. Six lines were generated, and the highest-expressing line was studied further. (J:108164)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:108164 Shimano H, et al., Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest. 1997 Mar 1;99(5):846-54
All:	2 reference(s)