Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ikzf1tm1.1Swnd
Name:	IKAROS family zinc finger 1; targeted mutation 1.1, Susan Winandy
MGI ID:	MGI:6273756
Synonyms:	Ikflox
Gene:	Ikzf1  Location: Chr11:11634980-11722926 bp, + strand  Genetic Position: Chr11, 7.02 cM
Alliance:	Ikzf1tm1.1Swnd page

Germline Transmission:	Earliest citation of germline transmission: J:268958
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 8, and a second loxP site downstream of the 3' untranslated region (UTR). The construct, also contains an FRT-flanked neomycin selection cassette.Flp-mediated recombination removed the FRT-flanked neo cassette. (J:268958)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ikzf1 Mutation:	30 strains or lines available

Original:	J:268958 Lyon de Ana C, et al., Lack of Ikaros Deregulates Inflammatory Gene Programs in T Cells. J Immunol. 2019;11
All:	1 reference(s)