Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd44M1Btlr
Name:	CD44 antigen; mutation 1, Bruce Beutler
MGI ID:	MGI:6268367
Synonyms:	Jialin
Gene:	Cd44  Location: Chr2:102641486-102732010 bp, - strand  Genetic Position: Chr2, 54.13 cM
Alliance:	Cd44M1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced G to T transversion at base pair 102,865,370 (v38) on chromosome 2, or base pair 36,300 in the GenBank genomic region NC_000068 encoding Cd44. The mutation corresponds to residue 475 in the mRNA sequence NM_009851 within exon 2 of 19 total exons. The mutation results in a glutamic acid (E) to aspartic acid (D) substitution at position 52 (E52D) in the CD44 protein. (J:267483) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd44 Mutation:	67 strains or lines available

Original:	J:267483 Zhong X, et al., Mutagenetix entry for Jialin. MGI Direct Data Submission. 2018;
All:	1 reference(s)