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Ppargm1Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Ppargm1Btlr
Name: peroxisome proliferator activated receptor gamma; mutation 1, Bruce Beutler
MGI ID: MGI:6199499
Synonyms: energy
Gene: Pparg  Location: Chr6:115360951-115490399 bp, + strand  Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced G to T transversion at base pair 115,451,044 (v38) on chromosome 6, or base pair 90,168 in the GenBank genomic region NC_000072 encoding Pparg. The mutation corresponds to residue 626 in the mRNA sequence NM_011146 within exon 4 of 7 total exons. The mutation results in an arginine (R) to leucine (L) substitution at residue 194 (R194L) in the PPAR protein. (J:265098)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pparg Mutation:  29 strains or lines available
References
Original:  J:265098 Chen Z, et al., Mutagenetix entry for energy. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory