Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Prdm16em1Snok
Name:	PR domain containing 16; endonuclease-mediated mutation 1, Hans-Willem Snoeck
MGI ID:	MGI:6196057
Synonyms:	delta13-fPrdm16-
Gene:	Prdm16  Location: Chr4:154400582-154721330 bp, - strand  Genetic Position: Chr4, 83.96 cM, cytoband E2
Alliance:	Prdm16em1Snok page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/cas9 endonuclease mediated genome editing is used to introduce a 13 base pair deletion in exon 2, creating a premature stop codon. (J:264335)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prdm16 Mutation:	72 strains or lines available

Original:	J:264335 Corrigan DJ, et al., PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature. J Clin Invest. 2018 Aug 1;128(8):3250-3264
All:	1 reference(s)