About   Help   FAQ
Zfp36tm1.1Pkov
Targeted Allele Detail
Summary
Symbol: Zfp36tm1.1Pkov
Name: zinc finger protein 36; targeted mutation 1.1, Pavel Kovarik
MGI ID: MGI:6163998
Synonyms: TTPfl
Gene: Zfp36  Location: Chr7:28076208-28078680 bp, - strand  Genetic Position: Chr7, 16.72 cM
Alliance: Zfp36tm1.1Pkov page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:262526
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by loxP sites and a neomycin cassette and a third loxP site were inserted downstream of the floxed exon 2. The selection cassette was excised by transiently transfecting ES cells with a cre recombinase-expressing construct. (J:262526)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfp36 Mutation:  16 strains or lines available
References
Original:  J:262526 Kratochvill F, et al., Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. Mol Syst Biol. 2011 Dec 20;7:560
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory