Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nfatc1em4(cre/ERT2)Bzsh
Name:	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; endonuclease-mediated mutation 4, Bin Zhou
MGI ID:	MGI:6163791
Synonyms:	Nfatc1-2A-CreER
Gene:	Nfatc1  Location: Chr18:80649420-80756286 bp, - strand  Genetic Position: Chr18, 53.66 cM, cytoband E4
Alliance:	Nfatc1em4(cre/ERT2)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Nfatc1em4(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nfatc1 (MGI:102469)   Mutation details: The line was generated by inserting a cDNA encoding Cre recombinase fused with a mutant form of estrogen receptor hormon-binding domaine C (ERT2) followed by an 2A peptide sequence into the 9th exon using the CRISPR/Cas9 technology. (J:262529)

Activity:	Tissue activity of this recombinase allele
Driver:	Nfatc1 (mouse) Summary of all recombinase alleles driven by Nfatc1. Comparative matrix view of recombinase activities Alliance mouse Nfatc1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfatc1 Mutation:	47 strains or lines available

Original:	J:262529 Zhang H, et al., Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. Cell Res. 2017 Sep;27(9):1157-1177
All:	2 reference(s)