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Hmox1tm1.1(CAG-EGFP)Rsto
Targeted Allele Detail
Summary
Symbol: Hmox1tm1.1(CAG-EGFP)Rsto
Name: heme oxygenase 1; targeted mutation 1.1, Roland Stocker
MGI ID: MGI:6160729
Synonyms: Hmox1tm1GFP/Rsto
Gene: Hmox1  Location: Chr8:75820249-75827217 bp, + strand  Genetic Position: Chr8, 35.59 cM, cytoband C1
Alliance: Hmox1tm1.1(CAG-EGFP)Rsto page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:262124
Parent Cell Line:  iTL BF1 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change, Reporter)
Mutation:    Insertion
 
Mutation detailsExons 2 through 5 were floxed. An inserted neomycin resistance cassette was removed by Flp-mediated recombination. When Cre recombinase is introduced, exons 2-5 will be excised and the 5-GFP and 3-GFP components will be joined and expressed. The expression of the GFP reporter will be driven by the pCAG promoter. (J:262124)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmox1 Mutation:  33 strains or lines available
References
Original:  J:262124 Newington D, et al., Hmox1 allele. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory